Strontium Ranelate Active Pharmaceutical Ingredient Terbinafine HCL
Strontium ranelate, a strontium(II) salt of ranelic acid, is a
medication for osteoporosis marketed as Protelos or Protos by
Servier. Studies indicate it can also slow the course of
osteoarthritis of the knee. The drug is unusual in that it both
increases deposition of new bone by osteoblasts and reduces the
resorption of bone by osteoclasts. It is therefore promoted as a
"dual action bone agent" (DABA).
|Product Name||Strontium ranelate|
acid strontium salt (1:2)|
|Packing||100G;500G;1Kg;25Kg(Export worthy packing)|
|Remark||For more details,please contact us|
Strontium ranelate is registered as a prescription drug in more
than 70 countries for the treatment of post-menopausal osteoporosis
to reduce the risk of vertebral and hip fractures. In the United
Kingdom, strontium ranelate is prescribed under the National Health
Service as a medicine for the treatment of post menopausal
- 2 major phase III clinical studies, SOTI (Spinal Osteoporosis
Therapeutic Intervention) and TROPOS (Treatment of Peripheral
Osteoporosis), were started in 2000 to investigate the efficacy of
strontium ranelate in reducing vertebral fractures and peripheral
fractures, including hip fractures.
- In the 3 years results, reported in 2004, strontium ranelate showed
significant reduction in vertebral fractures with 41% and hip
fractures with 36% compared with patients treated with placebo.
- The efficacy was sustained in 5 years data. The 5 years data
confirmed that strontium ranelate can reduce the vertebral
fractures significantly no matter the risk factors of the
osteoporotic women have.
Strontium ranelate shows anti-fracture efficacy in very old elderly
and osteopenic patients.
For 1% cream:
- for adults and children 12 years and older:
- wash the affected skin with soap and water and dry completely
- apply once a day to affected skin for 2 weeks or as directed by a
- wash hands after each use
- children under 12 years: ask a doctor
|Appearance||Off-white or primrose yellow crystalline powder|
|The spectrofram of the test solution corrsrponds to that of
|The retention time of the major peak of the test solution
corresponds to that of the RS|
|Turbidity of solution||Not more opalescent that reference solution class 1|
|Color of solution||Not more intensely colored that reference solution Y2|
|Loss of dying||20.0-23.5%|
|Chlorides||No more than 0.1%|
|Heavy metals(as Pb)||No more than 20ppm|
|Arsenic||No more than 0.0002%|
|Related substances(HPLC)||Any impurity NMT0.2%|
|Total impurities NMT0.5%|
|Solubility||Solute in 0.1mol/ hydrochloric acid solution, cery slightly solute
in water, practically solute in methanol or acetate|
|Assay(on dried basisi)||Over 99.0%|
Q1: Are you a manufacturer ?
A: Yes, our factory is located in Jiayu, Hubei, our lab located in
Wuhan. But we also do some trading business.
Q2: What`s your delivery
A: We send goods in 3 working day after receiving your payment by
DHL, FEDEX, TNT, EMS, AIR OR SEA as you request.
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC,
Q4: Why should I choose you?
A: Factory supply with the most compatitive price and high
Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp
give best offer. If you are good at bargaining, you can also enjoy
fun of bargaining. Just don't make it too hard!
Q6: How should I pay?
A: We accept all kinds of payment ways. such as alibaba trade
asssurance, T/T, West Union, Money Gram.
Q7: Do you provide free sample?
A: We can provide free sample of some chemicals and you just need
you to cover the delivery cost.